Research Article

miR-1258 Regulates Cell Proliferation and Cell Cycle to Inhibit the Progression of Breast Cancer by Targeting E2F1

Figure 2

Overexpression of miR-1258 affects the cell cycle and proliferation of BC cells. (a) Survival curves show the prognosis of patients with high expression of miR-1258 (red) and low expression of miR-1258 (blue). (b) GSEA enrichment analysis of miR-1258. (c) Expression of miR-1258 in BC cells after transfection with miR-1258 mimic. (d–g) Effects of miR-1258 overexpression on BC (d) cell proliferation, (e) growth, (f) apoptosis, and (g) cell cycle were detected. The experiments were repeated 3 times, .
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