Research Article

Jiao-Tai-Wan Ameliorates Depressive-Like Behavior through the A1R Pathway in Ovariectomized Mice after Unpredictable Chronic Stress

Figure 5

Effects of JTW on protein of A1R (a), ERK1/2 (b), and c-Fos (c) expression in the hippocampus. Mice were administered vehicle, JTW (3.3 and 6.6 mg/kg), or imipramine (10 mg/kg) once daily for 14 consecutive days. On the last day, mice were sacrificed after 30 min drug administration. Values are the with 6 mice in each group. Compared with vehicle-treated ovariectomized mice, #; compared with vehicle-treated ovariectomized mice subjected to chronic unpredictable stress, and .
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