Establishment and Investigation of a Multiple Gene Expression Signature to Predict Long-Term Survival in Pancreatic Cancer

Table 2

Characterization of the five candidate genes in hg 19 genome.

Gene symbol	Description	Expression status	Coordinate	value^a	^b	Coefficient^c
CHGA	Chromogranin A	Down tumor/normal	Chr14:93389445-93401638	<0.0001	18.35	-0.0481
COL17A1	Collagen type XVII alpha 1 chain	Up tumor/normal	Chr10:105791046-105845638	<0.0001	21.05	0.0402
ITGB6	Integrin subunit beta 6	Up tumor/normal	Chr2:160956182-161110349	<0.0001	16.13	0.0697
LAMC2	Laminin subunit gamma 2	Up tumor/normal	Chr1:183147952-183214262	0.00015	14.44	0.0021
S100P	S100 calcium binding protein P	Up tumor/normal	Chr4:6695566-6698897	0.0023	9.256	0.0063

^aDerived from the univariate Cox proportional hazards regression analysis in the training cohort (log-rank test). ^bDerived from the univariate Cox proportional hazards regression analysis in the training cohort (Chi² test). ^cDerived from the LASSO Cox regression analysis coefficients in the training cohort.