BioMed Research International / 2020 / Article / Fig 2

Clinical Study

Expression of GLUT3 and HIF-1α in Meningiomas of Various Grades Correlated with Peritumoral Brain Edema

Figure 2

Glucose transporter 3 (GLUT3) membrane immunostaining of meningioma cells. (a, b) High GLUT3 staining ((a) 40×; (b) 200×), GLUT3 in meningioma cells shows “map-like” multifocal staining with strong positive expression. (c, d) Moderate GLUT3 staining ((c) 40×; (d) 200×). (e, f) Low GLUT3 staining ((e) 40×; (f) 200×). Membrane-positive staining (black arrows) is evident in tumor cells. Cells with positive GLUT3 expression are separated from the intratumoral vascular network. Notably, we found GLUT3 expression in most lymphocytes ((a, c, and e) red arrows). (a–d) are regarded as positive results, whereas (e, f) are regarded as negative results.

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