Combinational Use of Antiplatelet Medication Sarpogrelate with Therapeutic Drug Rosuvastatin in Treating High-Cholesterol Diet-Induced Chronic Kidney Disease in ApoE-Deficient Mice

Figure 1

Morphological assessment of kidney tissue under each condition using H&E staining. Using conventional H&E staining, coronal sections of the kidney tissues were used for the histological evaluation of pathological changes in mice randomly divided into four groups: ApoE^−/− mice fed a normal diet (ApoE^−/− ND), ApoE^−/− mice fed a high-cholesterol diet (ApoE^−/− HD), ApoE^−/− mice fed rosuvastatin calcium+a high-cholesterol diet (ApoE^−/− HD+R), and ApoE^−/− mice fed rosuvastatin calcium+sarpogrelate+a high-cholesterol diet (ApoE^−/− HD+R+S), all for 8 weeks ( in each group).

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