Endocan and Lumican in Relation to Cardiometabolic Risk in a Pediatric Overweight and Obese Cohort: A Cross-Sectional Study
Table 5
Comparison between overweight and obese patients with metabolic syndrome and overweight and obese patients without metabolic syndrome according to IDF criteria.
Variable
Metabolic syndrome patients patients
Without metabolic syndrome patients patients
value
Boys (%)
6 (24%)
29 (67.4%)
0.001
Age (years)
11 (6)
8 (6)
0.005
Weight percentile
97th (5)
97th (4)
0.47
Waist percentile
95th (4)
95th (4)
0.074
Midarm circumference centile
95th (9)
95th (7)
0.89
BMI (kg/m2)
28 (10.10)
23.97 (5.10)
0.005
BMI percentile
98th (6)
98th (11)
0.80
BMI -score
2.08 (0.79)
2 (0.71)
0.79
WtHR
61.17 (10.85)
59 (5.23)
0.30
Total cholesterol (mg/dL)
160 (38)
167 (53)
0.93
LDL cholesterol (mg/dL)
99 (33)
107.5 (46)
0.73
HDL cholesterol (mg/dL)
35 (8)
48 (15)
<0.001
Triglyceride (mg/dL)
157 (91)
70 (47)
<0.001
Non-HDL cholesterol (mg/dL)
128 (34)
114 (46)
0.13
Triglyceride/HDL cholesterol ratio
4.14 (3.31)
1.65 (1.11)
<0.001
C-reactive protein (mg/dL)
0.39 (0.54)
0.38 (1.40)
0.98
Fasting glucose (mg/dL)
89 (8)
88 (12)
0.71
ASAT (UI/L)
23 (9)
23 (7)
0.96
ALAT (UI/L)
31 (30)
26 (12)
0.07
Alkaline phosphatase (UI/L)
232.5 (146)
243 (111)
0.53
Uric acid (mg/dL)
5.20 (2.2)
4.30 (2.2)
0.16
Obese (, %)
21 (84%)
38 (88.4%)
0.71
Insulin (mU/L)
14.81 (13.05)
7.75 (9.89)
0.083
HOMA-IR
3.15 (2.45)
1.69 (2.15)
0.085
Hypertension (%)
18 (72%)
14 (32.6%)
0.002
Systolic blood pressure percentile
90th (49)
50th (40)
0.026
Diastolic blood pressure percentile
90th (45)
50th (40)
0.040
Endocan (ng/mL)
2.04 (1.17)
3.06 (2.03)
0.003
Lumican (ng/mL)
14.29 (7.68)
11.40 (4.81)
0.06
Data are presented as median (interquartile range). BMI: body mass index; WtHR: waist to height ratio; ALAT: alanine aminotransferase; ASAT: aspartate aminotransferase; HDL: high-density lipoprotein; LDL: low-density lipoprotein; HOMA-IR: Homeostatic Model Assessment of Insulin Resistance. values were computed with Mann-Whitney tests for continuous variables and Fisher exact test for nominal variables.
