OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway

Figure 3

miR-210 targets 3UTR of EFNA3. (a) Binding site between miR-210 and EFNA3. (b–d) RT-PCR and Western blot showed that ephrinA3 in HUVECs changed when treated with miR-210 mimics, inhibitor, and their NC groups. Mimics of miR-210 could reduce ephrinA3, and the inhibitor could increase its level. , . (e) After treating with CAL27 CM, RT-PCR showed that mRNA expression of ephrinA3 in HUVECs was downregulated. . (f, g) Western blot showed that ephrinA3 protein in HUVECs was also reduced by treating with CAL27 CM. .

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