Research Article

[Retracted] HO-1/PINK1 Regulated Mitochondrial Fusion/Fission to Inhibit Pyroptosis and Attenuate Septic Acute Kidney Injury

Figure 7

HO-1/PINK1 pathway-alleviated LPS-induced pyroptosis in kidney. (a) Representative images of TUNEL staining. Scale bar: 100 μm. (b) Percentage of pyroptosis cells of tubular damage. (c) Western blot show the expression of caspase1 and IL-1β protein in kidney tissues of rats (A–C). (d) Real-time PCR shows the relative expression of (a) caspase1 mRNA and (b) IL-1β mRNA. Data are expressed as , . versus the WT control group, # versus the WT LPS group. PINK1KO: PTEN-induced putative kinase 1 knockout; LPS: lipopolysaccharide; Znpp: zinc protoporphyrin IX.
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