Research Article

Acacetin Suppresses IL-1β-Induced Expression of Matrix Metalloproteinases in Chondrocytes and Protects against Osteoarthritis in a Mouse Model by Inhibiting NF-κB Signaling Pathways

Figure 7

Acacetin inhibits MMP expression in vivo. (a) Immunohistochemical analysis of cartilage samples from knee joints for MMP-1, MMP-3, and MMP-13 at 6 weeks after ACLT surgery in mice in the sham, OA, H-acacetin, and L-acacetin groups ( per group). (b) Percentages of immune-positive cells in each group. , , and . .
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