Research Article

Epidural Labor Analgesia Is Associated with a Decreased Risk of the Edinburgh Postnatal Depression Scale in Trial of Labor after Cesarean: A Multicenter, Prospective Cohort Study

Table 1

Baseline maternal demographic and obstetric characteristics of parturients who completed the study.

CharacteristicTOLAC (CTRL)TOLAC (EXP)Statistical value value
N (all)n (%) or mean ± SDN (all)n (%) or mean ± SD

Mode of delivery160263<0.001
 Normal delivery111 (69.38%)225 (85.55%)
 Cesarean49 (30.63%)38 (14.45%)

Hospital name16026341.021<0.001
 MCH131 (81.88%)179 (68.06%)
 BA1 (0.62%)59 (22.43%)
 LG28 (17.50%)25 (9.51%)

General information
 Age (year)16032 ± 426232 ± 421481.50.667
 Gestational age (day)158272 ± 14260274 ± 1018846.50.157
 BMI (kg/m2)15826.45 ± 2.9325926.59 ± 3.0819040.50.234
 Maternal education >12 y116116 (72.96%)193193 (74.23%)0.819
 Husband education >12 y118118 (74.21%)207207 (79.62%)0.228
 Housewives15913 (8.18%)25921 (8.11%)1
 Family income (¥/mo)1462490.6960.706
  ≤10,00021 (14.38%)29 (11.65%)
  10,001–20,00053 (36.30%)90 (36.14%)
  >20,00072 (49.32%)130 (52.21%)

History of pregnancy and childbirth
Gravidity2.2640.322$
  27070 (44.59%)9898 (37.69%)
  36262 (39.49%)121121 (46.54%)
  >32525 (15.92%)4141 (15.77%)

History of depression and trauma1580 (0.00%)2624 (1.53%)0.302

Impact of childbirth on work or re-employment15810 (6.33%)26014 (5.38%)0.672

Maternity leave time1572580.031
 No1 (0.64%)6 (2.33%)
 Legal time93 (59.24%)178 (68.99%)
 Full-time63 (40.13%)74 (28.68%)

Anxiety and depression during pregnancy15866 (41.77%)26287 (33.21%)0.094

Cigarettes, alcohol, long-term medication1582 (1.27%)2611 (0.38%)0.56

Whether the husband is satisfied with the baby’s sex158144 (91.14%)260236 (90.77%)1

Caring health knowledge during pregnancy
 ① Routine obstetric examination158151 (95.57%)261251 (96.17%)0.801
 ② Attendance at childbirth classes during pregnancy15853 (33.54%)261121 (46.36%)0.011
 ③ Learn about parenting through cell phones or books158132 (83.54%)261224 (85.82%)0.573

Unplanned pregnancy15862 (39.24%)26290 (34.35%)0.346

Whether the maternal is the only child in one’s family15817 (10.76%)26036 (13.85%)0.449

Changes in marital relationship during pregnancy1572 (1.27%)2601 (0.38%)0.559

SAS15632.88 ± 6.2026131.14 ± 5.89237570.004

SSRS15645.74 ± 7.2726146.27 ± 5.8219937.50.723

MMSE15628.15 ± 1.1326128.10 ± 1.0621158.50.483

Prepartum Laboratory test
 HGB (g/L:115–150)159119.28 ± 15.05259116.68 ± 11.17226430.087
 PLT (125–350)159209.47 ± 55.51260210.03 ± 53.7020399.50.822

BMI: body mass index; SAS: Self-Rating Anxiety Scale; SSRS: Social Support Rating Scale; MMSE: mini-mental state examination; HGB: hemoglobin; PLT: platelet; ¥: Chinese Yuan; SDP: standard deviation. $Pearson’s chi-squared test; total income of husband and wife. Comparisons were made using Student’s t-test or Wilcoxon rank sum test for nonnormally distributed variables. Comparisons were made using Pearson’s chi-squared test and Fisher’s exact test for proportions.