Research Article

Trifolium Flavonoids Overcome Gefitinib Resistance of Non-Small-Cell Lung Cancer Cell by Suppressing ERK and STAT3 Signaling Pathways

Figure 3

The combination of TF and gefitinib synergistically activated the cleavage of PARP and caspases. (a) PC-9R cells were treated with 17 μM gefitinib alone or combine with 30 μg/ml TF for 24 h. Proteins were extracted and subjected to Western blotting assay to evaluate cleavage of caspases and PARP. (b) Quantitative analysis expression of proteins in (a). Data was presented by for three separate experiments. ; .
(a)
(b)