Genomic Analysis Reveals Novel Specific Metastatic Mutations in Chinese Clear Cell Renal Cell Carcinoma

Figure 5

Analysis of somatic alterations in the DDR pathway. (a) The frequency of DDR mutations across ccRCC patients with or without metastasis. (b) The frequency of specific mutated pathway in DDR. (c) Frequency of mutated DDR genes with known deleterious variants. HR: homology recombination; MMR: mismatch repair; NER: nucleotide excision repair; FA: Fanconi anemia; BER: base excision repair; NHEJ: nonhomology end joining; NP: nucleotide pool maintenance.

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