Research Article

Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma

Figure 1

Bioinformatics analysis related to PORCN. (a) Real-time PCR was used to detect the expression of PORCN in five cell lines. (b) Survival analysis of patients with renal cell carcinoma with high and low expression of PORCN by the Human Protein Atlas online tool. (c, d) The expression of PORCN in RCC specimens. (e, f) PORCN and related proteins, as well as their mutations in kidney cancer. (g, h) GO analysis and KEGG analysis on PORCN and its related genes.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)