[Retracted] 1H-Indole-3-Carbonyl-Thiazole-4-Carboxylic Acid Methyl Ester Blocked Human Glioma Cell Invasion via Aryl Hydrocarbon Receptor’s Regulation of Cytoskeletal Contraction

Figure 5

ITE binds to its receptor AHR, which mobilized it to enter the nucleus and triggered MYH9 gene. Reduced MYH9 level caused lowered cellular contractility, which is required for both amoeboid and mesenchymal migration.