A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Table 3
Tolerability assessment compared between the treatment side and placebo side (split-face study) during the maintenance phase ().
Variables
value
Treatment side
Placebo side
Patient evaluation
Erythema (-3)
Baseline
0.554
Week 4
0.659
Week 8
0.278
Week 12
0.351
Dryness (-3)
Baseline
0.212
Week 4
0.497
Week 8
0.133
Week 12
0.444
Scaling (-3)
Baseline
1.000
Week 4
1.000
Week 8
0.001
Week 12
0.622
Stinging/burning (-3)
Baseline
0.766
Week 4
0.204
Week 8
0.135
Week 12
0.485
Pruritus (-3)
Baseline
1.000
Week 4
0.371
Week 8
1.000
Week 12
1.000
Physician evaluation
Erythema (-3)
Baseline
0.302
Week 4
0.110
Week 8
0.182
Week 12
0.044
Dryness (-3)
Baseline
0.569
Week 4
1.000
Week 8
0.322
Week 12
0.420
Scaling (-3)
Baseline
0.322
Week 4
1.000
Week 8
0.420
Week 12
0.005
A value < 0.05 indicates statistical significance. Scoring: ,,, and .: number; SD: standard deviation.
