Research Article
Bioinformatics Analysis of Key Genes and circRNA-miRNA-mRNA Regulatory Network in Gastric Cancer
Table 1
15 hub DEGs in the PPI networks.
| Gene symbol | Official full name | Degree | Expression in GC |
| FN1 | Fibronectin 1 | 64 | Upregulation | COL1A1 | Collagen type I alpha 1 chain | 45 | Upregulation | COL1A2 | Collagen type I alpha 2 chain | 42 | Upregulation | COL3A1 | Collagen type III alpha 1 chain | 41 | Upregulation | CD44 | CD44 molecule (Indian blood group) | 40 | Upregulation | SPARC | Secreted protein acidic and cysteine rich | 36 | Upregulation | FBN1 | Fibrillin 1 | 36 | Upregulation | BGN | Biglycan | 36 | Upregulation | UBE2C | Ubiquitin-conjugating enzyme E2 C | 35 | Upregulation | SPP1 | Secreted phosphoprotein 1 | 35 | Upregulation | TIMP1 | TIMP metallopeptidase inhibitor 1 | 35 | Upregulation | THBS1 | Thrombospondin 1 | 34 | Upregulation | COL5A2 | Collagen type I alpha 2 chain | 32 | Upregulation | CXCL8 | C-X-C motif chemokine ligand 8 | 31 | Upregulation | CCNB1 | Cyclin B1 | 31 | Upregulation |
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