Research Article

Impact of Decreased Transmural Conduction Velocity on the Function of the Human Left Ventricle: A Simulation Study

Table 2

Parameters representing cardiovascular hemodynamics and LV performance in a steady cycle obtained from literature (Standard), from the model under control conditions (Control), and at TCV decreased to 50% (50% TCV).

StandardControl50% TCV

120 mmHg125 mmHg122 mmHg
80 mmHg80 mmHg79 mmHg
1780 mmHg/s1783 mmHg/s1751 mmHg/s
120 ml114 ml114 ml
40 ml36 ml37 ml
IVCD60 ml60 ms71 ms
EPD210 ml211 ms213 ms
EF67%69%67%
CO5600 ml/min5653 ml/min5538 ml/min
1.5 W1.51 W1.45 W

: systolic pressure in the aorta; : diastolic pressure in the aorta; : end-diastolic volume in the LV; : end-systolic volume in the LV; EPD: duration of ejection phase; EF: ejection fraction; CO: cardiac output; : power of the LV. The standard values of parameters were taken from [6, 21].