Long Noncoding RNA SOX2-OT: Regulations, Functions, and Roles on Mental Illnesses, Cancers, and Diabetic Complications

Table 4

The SNPs of SOX2-OT are associated with various diseases.

SNP	Mapped gene	Context	Disease/abnormality	PubMed ID
rs13096176	SOX2-OT	intron_variant	Schizophrenia	31740837 [69]
rs4855019	SOX2-OT	intron_variant	Schizophrenia	31740837 [69]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	31740837 [69]
rs35788479	SOX2-OT	intron_variant	General risk tolerance	30643258 [70]
rs114600294	SOX2-OT	intron_variant	General risk tolerance	30643258 [70]
rs833268	SOX2-OT	intron_variant	Male-pattern baldness	30573740 [71]
rs12632136	SOX2-OT	intron_variant	Reaction time	29844566 [72]
rs2216428	SOX2-OT	intron_variant	General cognitive disorder	29844566 [72]
rs1345417	SOX2-OT	intron_variant	Excessive hairiness	29895819 [73]
rs60733335	SOX2-OT	intron_variant	Hair color	30595370 [74]
rs2216427	SOX2-OT	intron_variant	Insomnia	30804565 [75]
rs12485391	SOX2-OT	intron_variant	Smoking status	30595370 [74]
rs2567646	SOX2-OT	intron_variant	General cognitive disorder	29844566 [72]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	25056061 [72]
rs1345417	SOX2-OT	intron_variant	Eyebrow thickness	30248107 [76]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	28991256 [77]
rs9859557	SOX2-OT	intron_variant	Schizophrenia	28991256 [77]
rs833270	SOX2-OT	intron_variant	Balding type 1	30595370 [74]
rs77025239	SOX2-OT	intron_variant	Educational attainment	30595370 [74]
rs1805207	SOX2-OT	intron_variant	Body mass index	30595370 [74]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	26198764 [78]
rs1805203	SOX2-OT	intron_variant	Schizophrenia	26198764 [78]
rs1878874	SOX2-OT	intron_variant	Schizophrenia	26198764 [78]
rs13086738	SOX2-OT	intron_variant	Eating disorder in individuals with bipolar disorder	26433762 [79]
rs4854912	SOX2-OT	intron_variant	Bipolar disorder and eating disorder	26433762 [79]
rs1345417	SOX2-OT	intron_variant	Monobrow	27182965 [80]
rs2718791	SOX2-OT	intron_variant	Smoking initiation	30643251 [81]
rs9859557	SOX2-OT	intron_variant	Schizophrenia	30285260 [82]
rs9859557	SOX2-OT	intron_variant	Schizophrenia	30285260 [82]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	30285260 [82]
rs9841616	SOX2-OT	intron_variant	Schizophrenia	30285260 [82]
rs75380963	SOX2-OT	exon_variant	Corneal astigmatism	30306274 [83]
rs77025239	SOX2-OT	intron_variant	Educational attainment	30038396 [84]
rs2718791	SOX2-OT	intron_variant	Educational attainment	30038396 [84]
rs77025239	SOX2-OT	intron_variant	Educational attainment	30038396 [84]
rs9841382	SOX2-OT	intron_variant	Self-reported risk-taking behavior	30271922 [85]
rs9841382	SOX2-OT	intron_variant	Self-reported risk-taking behavior	30181555 [86]
rs9841382	SOX2-OT	intron_variant	Self-reported risk-taking behavior	30181555 [86]
rs4133078	SOX2-OT	intron_variant	Height	30595370 [74]
rs7631379	SOX2-OT	intron_variant	Smoking initiation	30643251 [81]
rs34308817	SOX2-OT	intron_variant	Ankle injury	28957384 [87]
rs6443750	SOX2-OT	intron_variant	Body mass index	30595370 [74]
rs6443750	SOX2-OT	intron_variant	Body mass index	30239722 [88]
rs186834402	SOX2-OT	intron_variant	Interferon gamma levels	27989323 [89]
rs10937060	SOX2-OT	intron_variant	Night sleep phenotypes	27126917 [90]
rs9839776	SOX2-OT	intron_variant	Anorexia nervosa	24514567 [8]
rs4510419	SOX2-OT	intron_variant	Smoking initiation	30643251 [81]
rs9839776	SOX2-OT	intron_variant	Breast cancer	28240100 [31]
rs9839776	SOX2-OT	intron_variant	Recurrent miscarriage	31827385 [48]

Note: SNPs: single-nucleotide polymorphisms; OR: odds ratio.