TY - JOUR
A2 - Sun, Fengjie
AU - Tian, Ya
AU - Pu, Xiangdong
AU - Yu, Haoying
AU - Ji, Aijia
AU - Gao, Ranran
AU - Hu, Yating
AU - Xu, Zhichao
AU - Wang, Hualei
PY - 2020
DA - 2020/04/06
TI - Genome-Wide Characterization and Analysis of bHLH Transcription Factors Related to Crocin Biosynthesis in Gardenia jasminoides Ellis (Rubiaceae)
SP - 2903861
VL - 2020
AB - Crocins, enriched in Gardenia jasminoides fruits, have a pharmacological activity against central nervous system diseases, cardiovascular diseases, and cancer cell growth. The biosynthesis of crocins has been widely explored, but its regulatory mechanism remains unknown. Here, the basic helix-loop-helix (bHLH) transcription factors related to crocin biosynthesis were systematically identified on the basis of the genome of G. jasminoides. A total of 95 GjbHLH transcription factor genes were identified, and their phylogenetic analysis indicated that they could be classified into 23 subfamilies. The combination of gene-specific bHLH expression patterns, the coexpression analysis of biosynthesis genes, and the analysis of promoter sequences in crocin biosynthesis pathways suggested that nine bHLHs in G. jasminoides might negatively regulate crocin biosynthesis. This study laid a foundation for understanding the regulatory mechanism of crocin biosynthesis and the improvement and breeding of G. jasminoides varieties.
SN - 2314-6133
UR - https://doi.org/10.1155/2020/2903861
DO - 10.1155/2020/2903861
JF - BioMed Research International
PB - Hindawi
KW -
ER -