Research Article

CD44, IL-33, and ST2 Gene Polymorphisms on Hepatocellular Carcinoma Susceptibility in the Chinese Population

Table 7

The association of haplotype of each gene with hepatocellular cancer risk.

HaplotypeCase (%) Control (%) OR (95% CI)

rs187115-rs1929992-rs3821204
AAC227.91 (0.202)168.09 (0.150)0.0011.434 (1.152, 1.785)
AAG264.26 (0.234)343.55 (0.306)≤0.0010.692 (0.574, 0.834)
AGC168.53 (0.149)149.51 (0.133)0.2791.140 (0.899, 1.446)
AGG267.30 (0.237)310.86 (0.277)0.0270.808 (0.669, 0.977)
GAC44.16 (0.039)34.13 (0.030)0.2611.296 (0.823, 2.042)
GAG62.66 (0.055)44.23 (0.039)0.0731.431 (0.965, 2.122)
GGC38.40 (0.034)12.27 (0.011)≤0.0013.181 (1.664, 6.082)
GGG56.77 (0.050)59.36 (0.053)0.7740.947 (0.652, 1.376)
rs187115, rs3821204
AC396.22 (0.351)318.60 (0.284)≤0.0011.362 (1.139, 1.627)
AG531.77 (0.471)653.40 (0.582)≤0.0010.638 (0.540, 0.753)
GC82.77 (0.073)45.40 (0.040)≤0.0011.874 (1.292, 2.719)
GG119.23 (0.106)104.60 (0.093)0.3301.147 (0.870, 1.513)
rs187115, rs1929992
AA492.04 (0.435)511.85 (0.456)0.3210.919 (0.779, 1.086)
AG435.96 (0.386)460.15 (0.410)0.2380.903 (0.763, 1.070)
GA106.96 (0.095)78.15 (0.070)0.0311.396 (1.030, 1.893)
GG95.04 (0.08471.85 (0.064)0.0691.342 (0.976, 1.845)
rs1929992, rs3821204
AC271.98 (0.241)200.95 (0.179)0.0031.453 (1.184, 1.783)
AG327.02 (0.289)389.05 (0.347)0.0030.767 (0.642, 0.917)
GC207.02 (0.183)163.05 (0.145)0.0151.319 (1.054, 1.651)
GG323.98 (0.287)368.95 (0.329)0.0300.820 (0.686, 0.981)