CD44, IL-33, and ST2 Gene Polymorphisms on Hepatocellular Carcinoma Susceptibility in the Chinese Population
Table 8
False positive report probability values for associations between the risk of HCC and the frequency of genotypes and haplotypes of the CD44 gene and ST2 dene in an Chinese population.
Genotype/haplotype
OR (95% CI)
value
Statistical powera
Prior probability
0.25
0.1
0.01
0.001
0.0001
CD44 rs187115
AG/AA
1.359 (1.039-1.778)
0.025
0.764
0.091
0.232
0.796
0.971
0.997
GG/AA
2.443 (1.099-5.430)
0.028
0.116
0.429
0.693
0.961
0.996
1.000
AG+GG/AA
1.429 (1.101-1.855)
0.007
0.642
0.034
0.095
0.563
0.921
0.991
ST2 rs3821204
CG/GG
1.478 (1.144-1.910)
0.003
0.545
0.016
0.046
0.345
0.842
0.982
CC/GG
2.229 (1.564-3.177)
≤0.001
0.014
0.002
0.006
0.065
0.411
0.875
CG+CC/GG
1.648 (1.297-2.093)
≤0.001
0.220
0.001
0.002
0.020
0.168
0.668
aStatistical power was calculated using the number of observations in the subgroup and the OR and values in this table.
