Research Article

Significance of EGFR/HER2 Expression and PIK3CA Mutations in Giant Cell Tumour of Bone Development

Table 1

Univariate analysis of prognostic factors in GCTB.

CategoriesWith recurrenceWithout recurrenceTotal value

Cases, (%)15 (47%)17 (53%)32
Sex, (%)
 Male3 (20%)8 (47,1%)11 (34,4%)
 Female12 (80%)9 (52,9%)21 (65,6%)
Age group, (%)
 <20 ans1 (6,7%)3 (17,6%)4 (12,5%)
 20-39 ans10 (66,7%)8 (47,1%)18 (56,2%)
 ≥40 ans4 (26,7%)6 (35,3%)10 (31,2%)
Location, (%)
 Femur2 (13,3%)5 (29,4%)7 (21,9%)
 Tibia4 (26,7%)5 (29,4%)9 (28,1%)
 Radius7 (46,7%)3 (17,6%)10 (31,2%)
 Fibula1 (6,7%)2 (11,8%)3 (9,4%)
 Other locations1 (6,7%)2 (11,8%)3 (9,4%)
Campanacci’s grade, (%)
 I/II9 (60%)16 (94,1%)25 (78,1%)
 III6 (40%)1 (5,9%)7 (21,9%)
Jaffe-Lichtenstein grade, (%)
 I/II2 (14,3%)15 (83,3%)17 (53,1%)
 III12 (85,7%)3 (16,7%)15 (46,9%)
Surgical method, (%)
 Biopsy0 (0,0%)4 (23,5%)4 (12,5%)
 Intralesional curettage13 (86,7%)8 (47,1%)21 (65,6%)
 Wide resection2 (13,3%)5 (29,4%)7 (21,9%)

Significantly different by the chi-squared test.