BioMed Research International / 2020 / Article / Fig 1

Research Article

Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway

Figure 1

Apatinib inhibits the migration of HepG2, Hep3B, Huh7, and SMMC-7721 cells. Results of the wound healing assay of Hep3B, HepG2, Huh7, and SMMC-7721 cells following treatment with different doses of apatinib at 24 and 48 h (original magnification, ×200). Analysis of the relative migration rate curves showed that apatinib treatment inhibited the migration of Hep3B, HepG2, Huh7, and SMMC-7721 cells in a dose-dependent manner ( indicates and vs. 0 μmol/L (control)).

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