Review Article
The Novel Coronavirus Disease (COVID-19): A PRISMA Systematic Review and Meta-Analysis of Clinical and Paraclinical Characteristics
Table 5
Meta-analysis of laboratory findings before removing Fan et al. study.
| Group LAB test | Effect size and 95% confidence interval | Test of null (2-tail) | Heterogeneity | Outcome | Number of studies | Point estimate | Standard error | Variance | Lower limit | Upper limit | value | value | squared |
| CRP (mg/l) | 7 | 10.78 | 2.21 | 4.89 | 6.44 | 15.11 | 4.87 | 0.0000 | 30.63 | Lymphocytes (×109/l) | 7 | 1.00 | 0.13 | 0.02 | 0.73 | 1.26 | 7.48 | 0.0000 | 45.87 | WBC (×109/l) | 7 | 4.87 | 0.26 | 0.07 | 4.36 | 5.38 | 18.76 | 0.0000 | 0.00 | ALT (U/l) | 5 | 23.43 | 2.84 | 8.07 | 17.86 | 29.00 | 8.25 | 0.0000 | 0.00 | AST (U/l) | 5 | 25.84 | 2.47 | 6.08 | 21.01 | 30.68 | 10.48 | 0.0000 | 1.71 | Cr (μmol/l) | 5 | 69.90 | 3.87 | 14.97 | 62.32 | 77.48 | 18.06 | 0.0000 | 0.00 | D-dimer (μg/l) | 5 | 567.89 | 112.11 | 12568.89 | 348.15 | 787.62 | 5.07 | 0.0000 | 0.00 | Hemoglobin (g/l) | 5 | 131.71 | 3.37 | 11.38 | 125.10 | 138.32 | 39.05 | 0.0000 | 0.00 | LDH (U/l) | 5 | 258.56 | 26.39 | 696.51 | 206.84 | 310.29 | 9.80 | 0.0000 | 11.06 | Neutrophils (×109/l) | 5 | 3.20 | 0.31 | 0.09 | 2.59 | 3.80 | 10.38 | 0.0000 | 0.00 | Platelets (×109/l) | 5 | 166.39 | 10.92 | 119.17 | 145.00 | 187.79 | 15.24 | 0.0000 | 0.00 | Procalcitonin (ng/ml) | 5 | 0.17 | 0.08 | 0.01 | 0.01 | 0.32 | 2.15 | 0.0312 | 68.47 | Creatine kinase (U/l) | 4 | 110.18 | 19.92 | 396.72 | 71.14 | 149.22 | 5.53 | 0.0000 | 0.00 | Total bilirubin (mmol/l) | 4 | 8.36 | 1.08 | 1.16 | 6.25 | 10.48 | 7.76 | 0.0000 | 0.00 | Albumin (g/l) | 3 | 38.61 | 1.46 | 2.14 | 35.75 | 41.48 | 26.41 | 0.0000 | 44.52 | BUN (mmol/l) | 3 | 4.83 | 0.55 | 0.30 | 3.75 | 5.91 | 8.77 | 0.0000 | 0.00 | ESR | 2 | 40.79 | 24.93 | 621.75 | -8.08 | 89.67 | 1.64 | 0.1018 | 91.15 | Fibrinogen (g/l) | 2 | 3.21 | 0.22 | 0.05 | 2.78 | 3.64 | 14.71 | 0.0000 | 0.00 |
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