Review Article
The Novel Coronavirus Disease (COVID-19): A PRISMA Systematic Review and Meta-Analysis of Clinical and Paraclinical Characteristics
Table 6
Meta-analysis of laboratory findings after removing Fan et al. study.
| | Laboratory findings group (one study removed) | Effect size and 95% confidence interval | Test of null (2-tail) | Heterogeneity | | Outcome | Number of studies | Point estimate | Lower limit | Upper limit | value | value | squared |
| | CRP (mg/l) | 6 | 9.13 | 6.00 | 12.27 | 5.71 | 0.00 | 1.73 | | Lymphocytes (×109/l) | 6 | 0.99 | 0.78 | 1.20 | 9.20 | 0.00 | 37.93 | | WBC (×109/l) | 6 | 4.88 | 4.31 | 5.45 | 16.75 | 0.00 | 0.00 | | ALT (U/l) | 5 | 23.43 | 17.86 | 29.00 | 8.25 | 0.00 | 0.00 | | AST (U/l) | 5 | 25.84 | 21.01 | 30.68 | 10.48 | 0.00 | 1.71 | | Cr (μmol/l) | 5 | 69.90 | 62.32 | 77.48 | 18.06 | 0.00 | 0.00 | | D-dimer (μg/l) | 5 | 567.89 | 348.15 | 787.62 | 5.07 | 0.00 | 0.00 | | Hemoglobin (g/l) | 5 | 131.71 | 125.10 | 138.32 | 39.05 | 0.00 | 0.00 | | LDH (U/l) | 5 | 258.56 | 206.84 | 310.29 | 9.80 | 0.00 | 11.06 | | Neutrophils (×109/l) | 5 | 3.20 | 2.59 | 3.80 | 10.38 | 0.00 | 0.00 | | Platelets (×109/l) | 5 | 166.39 | 145.00 | 187.79 | 15.24 | 0.00 | 0.00 | | Procalcitonin (ng/ml) | 5 | 0.17 | 0.01 | 0.32 | 2.15 | 0.03 | 68.47 | | Creatine kinase (U/l) | 4 | 110.18 | 71.14 | 149.22 | 5.53 | 0.00 | 0.00 | | Total bilirubin (mmol/l) | 4 | 8.36 | 6.25 | 10.48 | 7.76 | 0.00 | 0.00 | | Albumin (g/l) | 3 | 38.61 | 35.75 | 41.48 | 26.41 | 0.00 | 44.52 | | BUN (mmol/l) | 3 | 4.83 | 3.75 | 5.91 | 8.77 | 0.00 | 0.00 | | Fibrinogen (g/l) | 2 | 3.21 | 2.78 | 3.64 | 14.71 | 0.00 | 0.00 |
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