Research Article

Relationship between Surgery under General Anesthesia and the Development of Dementia: A Systematic Review and Meta-Analysis

Figure 4

Forest plot for subgroups according to outcome definition: Alzheimer’s disease and all-cause dementia. An increased risk of dementia following general anesthesia was detected among all-cause dementia group, but with considerable heterogeneity. However, decreased risk of AD with general anesthesia exposure was detected among the studies with outcome definition limited to only Alzheimer’s disease.