Altered Bioavailability of Nitric Oxide and L-Arginine Is a Key Determinant of Endothelial Dysfunction in Preeclampsia

Table 1

Clinical and biochemical variables of the studied participants.

Parameters	Total ()	NP ()	PE ()	value
Age (years)				0.462
GA at sampling (weeks)				0.104
Nitric oxide (μmol/L)				0.010
L-Arginine (μmol/L)				0.034
ADMA (μmol/L)				<0.0001
3-Nitrotyrosine (mmol/L)				<0.0001
L-Arginine/ADMA ratio				<0.0001

PE: preeclamptic women; NP: normotensive pregnant women; GA: gestational age; BMI: body mass index; ADMA: asymmetric dimethylarginine. Data was presented as . The means of the clinical variables in PE were compared with NP using independent -test. Statistical significance level was considered at value < 0.05.