Research Article

Prognostic Value of Serum Osteopontin in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Table 1

Clinical characteristics of patients with IPF.

Clinical characteristicsControls (n = 20)AE-IPF patients (n = 32)S-IPF patients (n = 39) value (AE-IPF vs S-IPF)

Age (years)61.05 ± 6.5969.84 ± 8.2866.31 ± 7.930.097
Male85% (17)84% (27)97% (38)0.051
Smoker (%)0 (0)56% (18)44% (17)0.205
Corticosteroids (treated in hospital)0 (0)88% (28)13% (5)<0.001
FVC% predictedNA57.72 ± 14.2369.69 ± 16.430.016
DLCO% predictedNA35.61 ± 11.1552.05 ± 17.560.006
LDH (U/L)NA390.97 ± 152.74224.27 ± 36.60<0.001
CRP (mg/L)NA55.88 ± 55.0112.05 ± 21.01<0.001

; ; ; values were calculated using the Mann–Whitney test. CRP, C-reactive protein; LDH, lactate dehydrogenase; DLCO, diffusing lung capacity of carbon monoxide; FVC, forced vital capacity; NA, not applicable.