Research Article
Prognostic Value of Serum Osteopontin in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Table 1
Clinical characteristics of patients with IPF.
| Clinical characteristics | Controls (n = 20) | AE-IPF patients (n = 32) | S-IPF patients (n = 39) | value (AE-IPF vs S-IPF) |
| Age (years) | 61.05 ± 6.59 | 69.84 ± 8.28 | 66.31 ± 7.93 | 0.097 | Male | 85% (17) | 84% (27) | 97% (38) | 0.051 | Smoker (%) | 0 (0) | 56% (18) | 44% (17) | 0.205 | Corticosteroids (treated in hospital) | 0 (0) | 88% (28) | 13% (5) | <0.001 | FVC% predicted | NA | 57.72 ± 14.23 | 69.69 ± 16.43 | 0.016 | DLCO% predicted | NA | 35.61 ± 11.15 | 52.05 ± 17.56 | 0.006 | LDH (U/L) | NA | 390.97 ± 152.74 | 224.27 ± 36.60 | <0.001 | CRP (mg/L) | NA | 55.88 ± 55.01 | 12.05 ± 21.01 | <0.001 |
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; ; ; values were calculated using the Mann–Whitney test. CRP, C-reactive protein; LDH, lactate dehydrogenase; DLCO, diffusing lung capacity of carbon monoxide; FVC, forced vital capacity; NA, not applicable. |