Gender-Related and Hemispheric Effects in Cortical Thickness-Based Hemispheric Brain Morphological Network

Figure 1

Flowchart for the construction of a hemispheric morphological network using cortical thickness. Cortical thickness was extracted from the brain surface model using CIVET pipeline v2.1 (a). The regional distributions of the cortical thickness based on the upsampled AAL atlas were estimated (b). In (c), the hemispheric morphological networks were constructed using the Jensen–Shannon similarity (JSS) based on Jensen–Shannon divergence (JSD) as the edge. The global and local graph metrics of the network were calculated and integrated (d, e). Finally, the asymmetry indexes of the integrated global and local graph metrics of the network were calculated (f).