Identification of the DNA Replication Regulator MCM Complex Expression and Prognostic Significance in Hepatic Carcinoma

Table 2

KM plotter showing the correlation between different MCMs and survival outcomes in hepatic carcinoma.

Gene	RNAseq ID	Survival outcome	No. of cases	HR	95% CI	value	Low-expression cohort (months)	High-expression cohort (months)
MCM2	4171	OS	364	1.96	1.38-2.7	0.0001	71	38.3
		RFS	313	1.73	1.24-2.4	0.001	36.1	13.27
		PFS	366	1.87	1.34-2.6	0.0002	40.97	15.83
		DSS	357	2.34	1.49-3.6	0.00015	84.4	61.73
MCM3	4172	OS	364	1.8	1.25-2.5	0.0013	71	46.6
		RFS	313	1.81	1.28-2.5	0.00063	40.97	15.97
		PFS	366	1.86	1.36-2.5	0.000077	36.27	13.33
		DSS	357	2.47	1.5-4.06	0.00025	104.17	81.87
MCM4	4173	OS	364	1.9	1.31-2.7	0.00058	70.5	25.6
		RFS	313	1.51	1.06-2.1	0.02	34.4	13.27
		PFS	366	1.53	1.12-2.0	0.0068	29.3	12.87
		DSS	357	2.27	1.42-3.6	0.00043	84.4	49.67
MCM5	4174	OS	364	1.94	1.36-2.7	0.00019	70.5	30
		RFS	313	1.89	1.35-2.6	0.00018	37.23	12.87
		PFS	366	1.79	1.32-2.4	0.00014	29.77	11.47
		DSS	357	2.24	1.43-3.5	0.00031	84.4	56.17
MCM6	4175	OS	364	2.29	1.61-3.2	0.0000023	70.5	24.1
		RFS	313	2.08	1.49-2.9	0.000012	42.630	13.33
		PFS	366	2.11	1.56-2.8	0.00000059	36.27	11.97
		DSS	357	2.73	1.74-4.2	0.0000056	84.4	49.67
MCM7	4176	OS	364	1.93	1.36-2.7	0.00019	71	38.3
		RFS	313	1.78	1.23-2.5	0.0019	42.87	18.3
		PFS	366	1.86	1.33-2.6	0.00022	36.27	15.17
		DSS	357	2.64	1.52-4.5	0.00035	59.7	24.13

values ≤ 0.05 were considered statistically significant.