Research Article

Effect of BRCA1 on the Concurrent Chemoradiotherapy Resistance of Cervical Squamous Cell Carcinoma Based on Transcriptome Sequencing Analysis

Table 3

The significantly enriched analysis of DEGs between OV-BRCA1 and NC SiHa cells.

CategoryTermDescriptionAdjusted valueCount

BPGO:0051607Defense response to virus50
BPGO:0009615Response to virus57
BPGO:0060337Type I interferon signaling pathway29
BPGO:0071357Cellular response to type I interferon29
BPGO:0034341Response to interferon-gamma40
BPGO:0071346Cellular response to interferon-gamma38
BPGO:0034340Response to type I interferon29
BPGO:0060333Interferon-gamma-mediated signaling pathway27
BPGO:1903900Regulation of viral life cycle31
BPGO:0048525Negative regulation of viral process25
CCGO:0000786Nucleosome31
CCGO:0044815DNA packaging complex31
CCGO:0032993Protein-DNA complex36
CCGO:0071556Integral component of lumenal side of endoplasmic reticulum membrane12
CCGO:0098553Lumenal side of endoplasmic reticulum membrane12
CCGO:0005788Endoplasmic reticulum lumen41
CCGO:0005925Focal adhesion49
CCGO:0000788Nuclear nucleosome12
CCGO:0005924Cell-substrate adherens junction49
CCGO:0030055Cell-substrate junction49
MFGO:0016763Transferase activity transferring pentosyl groups13
MFGO:0003950NAD+ ADP-ribosyltransferase activity9
MFGO:0002020Protease binding20
MFGO:0005125Cytokine activity29