BioMed Research International / 2020 / Article / Fig 4

Research Article

Wubeizi Ointment Suppresses Keloid Formation through Modulation of the mTOR Pathway

Figure 4

The effect of Wubeizi ointment on fibroblast proliferation and apoptosis. (a) The inhibitory effect of Wubeizi ointment on fibroblast proliferation. After IGF-1 and/or Wubeizi ointment treatment, the proliferation of keloid fibroblasts at specific time points was detected by the MTT assay. OD valves were read on an enzyme-linked immunoassay analyzer and presented as . ; , . (b) The effect of Wubeizi ointment on fibroblast apoptosis. After IGF-1 and/or Wubeizi ointment treatment, the apoptosis of keloid fibroblasts was detected by flow cytometry. Representative pictures are shown. Dot intensities in both Q2 and Q3 regions indicated the number of apoptotic cells.
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