A Study on the Immunohistochemical Expressions of Leptin and Leptin Receptor in Clear Cell Renal Cell Carcinoma

Table 2

Expressions of leptin and leptin receptor in tumour tissue with correlation to cohort characteristics and tumour features.

Variables	Leptin						Leptin receptor
	Overall expression (%) (cytoplasm+membranous)			Nuclear expression (%)			Overall expression (%) (cytoplasm+membranous)			Nuclear expression (%)
Percentages	Low	High	value	Low	High	value	Low	High	value	Low	High	value
BMI
Normal	10.0	16.7	0.097	20.0	13.3	0.384	18.3	11.7	0.760	21.7	18.3	0.426
Obese	26.7	15.0		25.0	28.3		21.7	16.7		20.0	26.7
T stage
1	20.0	16.7	0.342	18.3	25.0	0.414	15.0	13.3	0.212	21.7	18.3	0.414
2	11.7	3.3		15.0	5.0		8.3	8.3		8.3	11.7
3	5.0	11.7		10.0	11.7		15.0	6.7		11.7	13.3
4	0.0	0.0		1.7	0.0		1.7	0.0		0.0	1.7
N stage
N0	33.3	26.7	0.523	41.7	33.3	0.084	38.3	25.0	0.374	36.7	36.7	0.483
N1	3.3	5.0		3.3	8.3		1.7	3.3		5.0	8.3
Metastasis
M0	30.0	28.3	0.587	33.3	33.3	0.582	28.3	20.0	0.814	35.0	36.7	0.836
M1	6.7	3.3		11.7	8.3		11.7	8.3		6.7	8.3
Clinical stage
I	18.3	11.7	0.242	16.7	18.3	0.683	13.3	6.7	0.859	20.0	13.3	0.420
II	11.7	6.7		15.0	5.0		8.3	10.0		8.3	13.3
III	3.3	10.0		5.0	8.3		10.0	3.3		6.7	11.7
IV	3.3	3.3		8.3	10.0		8.3	8.3		6.7	6.7
Grade
Grades 1-2	28.3	18.3	0.188	28.3	30.0	0.496	26.7	18.3	0.912	26.7	28.3	0.922
Grades 3-4	8.3	13.3		16.7	11.7		13.3	10.0		15.0	16.7