Hepatoprotective Activity of Leptadenia hastata (Asclepiadaceae) on Acetaminophen-Induced Toxicity in Mice: In Vivo Study and Characterization of Bioactive Compounds through Molecular Docking Approaches

<div>Micrographs of liver sections of mice treated with different doses of the L. hastata stem decoction (magnification ×100). (a) APAP-treated mice (negative control). Black arrows show high leukocyte infiltration around the centrilobular vein (CV); (b) normal control; positive control—(c) 250 mg/kg APAP+silymarin (50 mg/kg), (d) 250 mg/kg APAP+L. hastata stem decoction (100 mg/kg), (e) 250 mg/kg APAP+L. hastata stem decoction (250 mg/kg), and (f) 250 mg/kg APAP+L. hastata stem decoction (500 mg/kg).</div>

BioMed Research International

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Figure 5

Figure 5: Hepatoprotective Activity of Leptadenia hastata (Asclepiadaceae) on Acetaminophen-Induced Toxicity in Mice: In Vivo Study and Characterization of Bioactive Compounds through Molecular Docking Approaches

Figure 5 | Hepatoprotective Activity of Leptadenia hastata (Asclepiadaceae) on Acetaminophen-Induced Toxicity in Mice: In Vivo Study and Characterization of Bioactive Compounds through Molecular Docking Approaches 