Hepatoprotective Activity of Leptadenia hastata (Asclepiadaceae) on Acetaminophen-Induced Toxicity in Mice: In Vivo Study and Characterization of Bioactive Compounds through Molecular Docking Approaches

Table 1

Effects of L. hastata aqueous decoction on the histopathological grade values induced by chronic APAP administration.

Group		Histopathological score
APAP	5	^≠≠
Normal	5
APAP 250 mg/kg+silymarin at 50 mg/kg	5
APAP 250 mg/kg+L. hastata at 100 mg/kg	5
APAP 250 mg/kg+L. hastata at 250 mg/kg	5
APAP 250 mg/kg+L. hastata at 500 mg/kg	5

≠≠ indicates significant difference () when compared to normal control and ∗ or ∗∗ indicates significant values at and , respectively, when compared to the APAP group.