BioMed Research International / 2020 / Article / Fig 4

Research Article

Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide

Figure 4

Crocin relieved corticosterone induced PC12 injury by regulating PACAP-mediated ERK and CREB signaling pathways. (a) Hoechst 33258 staining and observation of PC12 cells with fluorescence microscope. (b) Effect of crocin in cell viability using MTT assay. ANOVA, , . (c-f) PACAP, ERK, and CREB were analyzed by immunoblotting. ANOVA, , ; ANOVA, , ; ANOVA, , . Data are expressed as (). and versus the control group; and versus CORT group.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.