Treatment with Hyaluronic Acid and Collagen-Polyvinylpyrrolidone Improves Extracellular Matrix Assembly for Scarring after Tracheal Resection

Figure 9

Immunohistochemical detection of collagen type III in the lamina propria (LP) and submucosa (SM) from tracheal tissue. (b) Group I (control) and (f) group V (mitomycin C) showing immunostaining in strong red of the expression of collagen type III. (c) Group II (hyaluronic acid), (d) group III (collagen-PVP), and (e) group IV (mixture of hyaluronic acid+collagen-PVP) showing light red immunostaining which indicates the expression of collagen type III. (a) Presurgery samples. (g) Tracheal tissue as a negative control. (h) The human placenta was the positive control.

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