Ensemble Learning Prediction of Drug-Target Interactions Using GIST Descriptor Extracted from PSSM-Based Evolutionary Information

Table 2

5-fold cross-validation results were generated through the proposed method on the enzyme dataset.

Testing set	Accuracy (%)	Precision (%)	Sensitivity (%)	MCC (%)	AUC	AUPR
1	88.89	89.70	87.86	80.24	0.9570	0.8579
2	89.66	91.07	88.14	81.45	0.9450	0.8920
3	88.63	88.87	88.10	79.85	0.9444	0.8803
4	89.91	91.97	87.20	81.83	0.9538	0.8728
5	89.15	91.88	86.13	80.62	0.9391	0.8788
Average	89.25 ± 0.53	90.70 ± 1.37	87.48 ± 0.85	80.80 ± 0.83	0.9479 ± 0.0074	0.8763 ± 0.0125