Review Article
Expression Level and Clinical Significance of NKILA in Human Cancers: A Systematic Review and Meta-Analysis
Table 1
Clinical characteristics of the included studies.
| Surname (year) | Country | Cancer type | Sample size | High | Low | Cutoff (high/low) | Detection method | Clinical features | Quality score | References |
| Fei Tao (2018) | China | Rectal cancer | 152 | 76 | 76 | Median | qRT-PCR | C; T; H | 7 | [19] | Guodong Zhang (2019) | China | Osteosarcoma | 60 | 30 | 30 | Median | qRT-PCR | C; L | 6 | [25] | Tao Yang (2017) | China | Laryngeal cancer | 65 | 33 | 32 | Median | qRT-PCR | C; L; H | 7 | [17] | Zhiliang Lu (2017) | China | NSCLC | 110 | 55 | 55 | Median | qRT-PCR | C; H; T; L | 8 | [26] | Wei Huang (2016) | China | TSCC | 96 | 44 | 52 | Mean | qRT-PCR | C; H; T | 7 | [20] | Peng Jiang (2019) | China | CRC | 173 | 71 | 102 | Mean | qRT-PCR | C; H; T | 6 | [21] | Shun Ke (2018) | China | ESCC | 137 | 68 | 69 | Median | qRT-PCR | C; H | 8 | [16] | Ronggao Chen (2020) | China | HCC | 90 | 45 | 45 | Median | qRT-PCR | H | 7 | [24] | Xiaolan Yu (2018) | China | HCC | 54 | 27 | 27 | Median | qRT-PCR | NA | 7 | [22] |
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NSCLC: non-small-cell lung cancer; TSCC: tongue squamous cell carcinoma; CRC: colorectal cancer; ESCC: esophageal squamous cell carcinoma; HCC: hepatocellular carcinoma; C: clinical stage; H: histological grade; L: lymph node metastasis; T: tumor invasion depth; NA: not available.
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