Research Article
Elevated Interleukin-6 Levels within 72 Hours Post Admission Are Associated with Disease Progression in Nonseptic Critically Ill Children
Table 1
Clinical characteristics of nonseptic critically ill children in PICU with or without clinical recovery by day 4.
| | Characteristics | Clinical symptoms relieved at day 4 | value | | Yes () | No () |
| | Age (years), median (IQR) | 3.1 (0.4~8.1) | 3.6 (0.4~8.3) | 0.8472 | | Male/female | 27/15 | 17/6 | 0.93 | | Diagnostic at PICU admission | | Respiratory | 15/42 (35.7) | 8/23 (34.8) | 0.9472 | | Gastrointestinal | 10/42 (23.8) | 5/23 (21.7) | 0.8583 | | Cardiovascular | 9/42 (21.4) | 4/23 (17.3) | 0.7068 | | Neurological | 6/42 (14.3) | 4/23 (17.3) | 0.7503 | | Other | 2/42 (4.8) | 2/23 (8.7) | 0.5432 | | PCIS scores (IQR) | 86 (80-94) | 80 (76-90) | 0.095 | | IgG (mg/L) (IQR) | 8.26 (5.56-10.3) | 10.5 (4.965-19.55) | 0.4587 | | IgA (mg/L) (IQR) | 0.82 (0.38-1.27) | 0.65 (0.49-1.87) | 0.5965 | | IgM (mg/L) (IQR) | 0.88 (0.62-1.55) | 1.02 (0.57-1.51) | 0.9327 | | C3 (mg/L) (IQR) | 0.83 (0.72-0.98) | 0.81 (0.63-1.01) | 0.9663 | | C4 (mg/L) (IQR) | 0.18 (0.14-0.23) | 0.19 (0.11-0.28) | 0.6424 | | CD3% (IQR) | 63.06 (55.65-74.72) | 70.21 (61.92-77.22) | 0.0716 | | CD4 (%) (IQR) | 31.69 (23.76-39.83) | 35.82 (27.32-46.63) | 0.2482 | | CD8 (%) (IQR) | 23.01 (16.93-29.32) | 30.23 (19.64-37.26) | 0.0866 | | B cell (%) (IQR) | 26.98 (19.83-34.16) | 22.26 (13.72-26.52) | 0.0578 | | NK cell (%) (IQR) | 5.03 (2.39-8.86) | 5.23 (3.14-13.17) | 0.3278 | | PICU stay (days) (median, IQR) | 5.00 (3.00-7.00) | 9.00 (3.00-12.00) | 0.0124 |
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