Anion Gap Was Associated with Inhospital Mortality and Adverse Clinical Outcomes of Coronary Care Unit Patients

Table 3

The association between AG and inhospital all-cause mortality.

	AG (mmol)
	OR (95% CI)	value	for trend
Model 1			<0.001
Quartile 1:	Ref
Quartile 2:	1.01 (0.74-1.38)	0.958
Quartile 3:	1.40 (1.03-1.90)	0.029
Quartile 4:	2.72 (2.08-3.55)	<0.001
Continuous	1.13 (1.10-1.16)	<0.001
Model 2			<0.001
Quartile 1:	Ref
Quartile 2:	1.02 (0.75-1.40)	0.891
Quartile 3:	1.40 (1.03-1.91)	0.031
Quartile 4:	2.78 (2.12-3.63)	<0.001
Continuous	1.14 (1.11-1.16)	<0.001
Model 3
Quartile 1:	Ref		<0.001
Quartile 2:	1.02 (0.72-1.45)	0.897
Quartile 3:	1.22 (0.86-1.73)	0.258
Quartile 4:	1.49 (1.07-2.09)	0.019
Continuous	1.06 (1.02-1.09)	0.001

Models were derived from binary logistic regression analysis. Model 1: unadjusted. Model 2: adjusted for age, gender, and race. Model 3: adjusted for age, gender, race, body mass index, coronary heart disease, acute myocardial infarction, atrial fibrillation, ventricular arrhythmias, third-degree atrioventricular block, congestive heart failure, primary cardiomyopathy, valve disease, endocarditis, cardiogenic shock, hypertension, diabetes, hypercholesterolemia, respiratory failure, chronic kidney disease, chronic liver disease, chronic lung disease, malignancy, autoimmune disease, prior myocardial infarction, prior stroke, oral anticoagulants, statin, vasopressin, angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, antiplatelet, blood nitrogen urea, white blood cell, sodium, and creatinine. Abbreviation: AG: anion gap; OR: odds ratio; CI: confidence interval.