Association between APOBEC3H-Mediated Demethylation and Immune Landscape in Head and Neck Squamous Carcinoma

Figure 5

Biological functions of APOBEC3H in HNSC. (a) The heatmap of APOBEC3H-specific mRNAs (columns, individual samples; rows, genes; red, high expression levels; blue, low expression levels). (b) Venn diagram of the intersecting DEGs and DMGs from APOBEC3H-specific methylation genes (red, DEGs; blue, DMGs; cross area, both DEGs and DMGs). (c) The KEGG analysis of the common 189 genes in both gene clusters. (d) The heatmap of APOBEC3H-coexpressed genes identified by TIMER (-score, expression levels of each individuals; Group, expression levels of APOBEC3H). (e) Venn diagram of the intersecting genes from DMGs, DEGs, and APOBEC3H-coexpressed genes (diff_cor). (f) The KEGG analysis of the common 169 genes in above three gene clusters.

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