Research Article
Coniferyl Aldehyde Inhibits the Inflammatory Effects of Leptomeningeal Cells by Suppressing the JAK2 Signaling
Figure 2
MCM increases the expression of proinflammatory mediators in leptomeningeal cells, which is suppressed by AG490. (a, b) TNF-α mRNA and protein levels in leptomeningeal cells after 12 h of treatment were measured by RT-qPCR and ELISA; (c, d) IL-6 mRNA and protein levels in leptomeningeal cells after 12 h of treatment were measured by RT-qPCR and ELISA; (e, f) IL-1β mRNA and protein levels in leptomeningeal cells after 12 h of treatment were measured by RT-qPCR and ELISA. Each column and bar represent the (, each). Asterisks indicate a statistically significantly difference from the value in corresponding group (P<0.01; ).
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