Research Article
The PARK2 Mutation Associated with Parkinson’s Disease Enhances the Vulnerability of Peripheral Blood Lymphocytes to Paraquat
Table 3
Clinical features of patients in the study sample.
| Clinical feature | Patients without mutation | Patients with Parkin mutation |
| Number | 5 [3/2]a | 5 [4/1]a | Age at disease onset (years) | 32.80 ± 2.39 | 29.80 ± 8.20 | Disease duration (years) | | | Bradykinesia | 5 (100)b | 5 (100)b | Rigidity | 5 (100)b | 5 (100)b | Resting tremor | 2 (40)b | 3 (66.7)b | Postural tremor | 1 (20)b | 2 (40)b | Shuffling gait | 2 (40)b | 2 (40)b | Postural instability | 0 (0)b | 1 (20)b | Hyperreflexia | 0 (0)b | 2 (40)b | Diurnal fluctuations | 1 (20)b | 2 (40)b | Foot dystonia | 0 (0)b | 3 (66.7)b | UPDRS III score at last exam (off state) | 19.20 ± 4.32 | 19.00 ± 5.87 |
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aValues in square brackets indicate ratios. bValues in parentheses indicate percentages. |