BioMed Research International / 2020 / Article / Fig 3

Research Article

Icariin Ameliorates Lower Back Pain in Rats via Suppressing the Secretion of Cytokine-Induced Neutrophil Chemoatractant-1

Figure 3

Administration of ICA suppressed the expression of pain-related peptides such as SP and CGRP. (a) At the end of observation, the expression of SP was significantly increased in the puncture+saline group when compared with the sham-surgery group; however, treatment with ICA significantly suppressed the overexpression. (b) A similar trend was seen in the expression of CGRP (<0.05, <0.01, and <0.001 when compared between each group. The data are shown as . ~5 for each group. One-way ANOVA and Tukey’s multiple comparison test were used for statistical analysis).

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