Icariin Ameliorates Lower Back Pain in Rats via Suppressing the Secretion of Cytokine-Induced Neutrophil Chemoatractant-1
Treatment with ICA inhibited the expression of CINC-1. (a) Compared with the sham-surgery group, puncture of the disc resulted in a significant increase in CINC-1, but ICA was able to suppress the production of CINC-1 in a dose-response manner. (b) The gene expression was also decreased with ICA treatment when compared with the puncture+saline group (<0.001 when compared between each group. The data are shown as . for each group. One-way ANOVA and Tukey’s multiple comparison test were used for statistical analysis).
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