Research Article

Determinants of Neonatal Jaundice among Neonates Admitted to Neonatal Intensive Care Unit in Public General Hospitals of Central Zone, Tigray, Northern Ethiopia, 2019: a Case-Control Study

Table 4

Determinants of neonatal jaundice at neonatal intensive care units in public general hospitals of central zone, Tigray, 2019.

VariablesCategoryCase ()Control ()COR (95% CI)AOR (95% CI)

Obstetric complicationYes20 (22%)17 (9.4%)2.72 (1.34-5.49)5.77 (1.85-17.98)
No71 (78%)164 (90.6%)11
Birth weightLBW23 (25.3%)27 (14.9%)2.04 (1.09-3.85)4.27 (1.58-11.56)
Normal60 (65.9%)144 (79.6%)11
Macrocosmic8 (8.8%)10 (5.5%)1.4 (0.61-2)4.56 (0.396-52.14)
Birth asphyxiaYes20 (22%)40 (22.1%)1.26 (0.67-2.39)4.83 (1.62-14.4)
Unknown27 (29.7%)30 (16.6%)2.27 (1.21-4.25)2.36 (0.86-6.48)
No44 (48.4%)111 (61.3%)11
CephalohematomaYes16 (17.6%)12 (6.6)3.0 (1.36-6.66)4.86 (1.173-20.131)
No75 (82.4%)169 (93.4%)11
RH incompatibilityYes16 (17.6%)7 (5.1%)3.96 (1.56-10.07)5.45 (1.58-18.74)
No75 (82.4%)130 (94.9%)11
BreastfeedingNot feeding11 (12.1%)24 (13.3%)2.37 (0.77-7.32)1.52 (0.29-7.93)
Breast feed74 (81.3%)126 (69.6%)3.03 (1.21-7.62)6.11 (1.71-21.89)
Formula feed6 (6.6%)31 (17.1%)11
PolycythemiaYes21 (23.1%)13 (7.2%)3.88 (1.84-8.17)7.32 (2.51-21.31)
No70 (76.9%)168 (92.8%)11
Hepatitis B statusUnknown24 (26.4%)90 (49.7%)0.34 (0.19-0.59)0.15 (0.06-0.37)
Reactive7 (7.7%)15 (8.3%)0.59 (0.23-1.54)0.35 (0.03-1.47)
Nonreactive60 (65.9%)76 (42%)11
Neonatal sepsisYes43 (47.3%)58 (32%)1.9 (1.1-3.18)1.74 (0.79-3.82)
No48 (52.7%)123 (68%)11
Mode of deliveryInstrumental14 (15.4%)19 (10.5%)1.76 (0.83-3.73)0.97 (0.20-4.65)
c/s17 (18.7%)19 (10.5%)2.13 (1.04-4.38)0.75 (0.25-2.25)
SVD60 (65.9%)143 (79%)11
Maternal bloodUnknown24 (26.4%)17 (9.4%)2.47 (1.17-5.20)3.26 (0.98-10.74)
B18 (19.8%)39 (21.6%)15 (4.5-49.2)0.36 (0.01-2.06)
AB9 (9.9%)20 (11%)4.7 (1.3-17.9)0.47 (0.07-3.05)
O5 (5.5%)42 (23.2%)0.21 (0.08-0.57)0.10 (0.02-0.38)
A36 (39.6%)63 (34.8%)11
Blood group neonateUnknown5 (5.5%)46 (25.4%)0.12 (0.04-0.34)4.76 (0.52-43.39)
O24 (26.4%)25 (13.8)1.09 (0.53-2.21)1.12 (0.41-3.03)
AB9 (9.9%)10 (5.5%)0.3 (0.15-0.61)0.57 (0.14-2.28)
B15 (16.5%)57 (31.5%)0.3 (0.15-0.61)0.22 (0.08-0.61)
A38 (41.8%)43 (23.8%)11

N.B indicates the determinant of neonatal jaundice at value <0.05. LBW: low birth weight, c/s: cesarean section, SVD: spontaneous vaginal delivery.