Determinants of Neonatal Jaundice among Neonates Admitted to Neonatal Intensive Care Unit in Public General Hospitals of Central Zone, Tigray, Northern Ethiopia, 2019: a Case-Control Study
Table 4
Determinants of neonatal jaundice at neonatal intensive care units in public general hospitals of central zone, Tigray, 2019.
Variables
Category
Case ()
Control ()
COR (95% CI)
AOR (95% CI)
Obstetric complication
Yes
20 (22%)
17 (9.4%)
2.72 (1.34-5.49)
5.77 (1.85-17.98)
No
71 (78%)
164 (90.6%)
1
1
Birth weight
LBW
23 (25.3%)
27 (14.9%)
2.04 (1.09-3.85)
4.27 (1.58-11.56)
Normal
60 (65.9%)
144 (79.6%)
1
1
Macrocosmic
8 (8.8%)
10 (5.5%)
1.4 (0.61-2)
4.56 (0.396-52.14)
Birth asphyxia
Yes
20 (22%)
40 (22.1%)
1.26 (0.67-2.39)
4.83 (1.62-14.4)
Unknown
27 (29.7%)
30 (16.6%)
2.27 (1.21-4.25)
2.36 (0.86-6.48)
No
44 (48.4%)
111 (61.3%)
1
1
Cephalohematoma
Yes
16 (17.6%)
12 (6.6)
3.0 (1.36-6.66)
4.86 (1.173-20.131)
No
75 (82.4%)
169 (93.4%)
1
1
RH incompatibility
Yes
16 (17.6%)
7 (5.1%)
3.96 (1.56-10.07)
5.45 (1.58-18.74)
No
75 (82.4%)
130 (94.9%)
1
1
Breastfeeding
Not feeding
11 (12.1%)
24 (13.3%)
2.37 (0.77-7.32)
1.52 (0.29-7.93)
Breast feed
74 (81.3%)
126 (69.6%)
3.03 (1.21-7.62)
6.11 (1.71-21.89)
Formula feed
6 (6.6%)
31 (17.1%)
1
1
Polycythemia
Yes
21 (23.1%)
13 (7.2%)
3.88 (1.84-8.17)
7.32 (2.51-21.31)
No
70 (76.9%)
168 (92.8%)
1
1
Hepatitis B status
Unknown
24 (26.4%)
90 (49.7%)
0.34 (0.19-0.59)
0.15 (0.06-0.37)
Reactive
7 (7.7%)
15 (8.3%)
0.59 (0.23-1.54)
0.35 (0.03-1.47)
Nonreactive
60 (65.9%)
76 (42%)
1
1
Neonatal sepsis
Yes
43 (47.3%)
58 (32%)
1.9 (1.1-3.18)
1.74 (0.79-3.82)
No
48 (52.7%)
123 (68%)
1
1
Mode of delivery
Instrumental
14 (15.4%)
19 (10.5%)
1.76 (0.83-3.73)
0.97 (0.20-4.65)
c/s
17 (18.7%)
19 (10.5%)
2.13 (1.04-4.38)
0.75 (0.25-2.25)
SVD
60 (65.9%)
143 (79%)
1
1
Maternal blood
Unknown
24 (26.4%)
17 (9.4%)
2.47 (1.17-5.20)
3.26 (0.98-10.74)
B
18 (19.8%)
39 (21.6%)
15 (4.5-49.2)
0.36 (0.01-2.06)
AB
9 (9.9%)
20 (11%)
4.7 (1.3-17.9)
0.47 (0.07-3.05)
O
5 (5.5%)
42 (23.2%)
0.21 (0.08-0.57)
0.10 (0.02-0.38)
A
36 (39.6%)
63 (34.8%)
1
1
Blood group neonate
Unknown
5 (5.5%)
46 (25.4%)
0.12 (0.04-0.34)
4.76 (0.52-43.39)
O
24 (26.4%)
25 (13.8)
1.09 (0.53-2.21)
1.12 (0.41-3.03)
AB
9 (9.9%)
10 (5.5%)
0.3 (0.15-0.61)
0.57 (0.14-2.28)
B
15 (16.5%)
57 (31.5%)
0.3 (0.15-0.61)
0.22 (0.08-0.61)
A
38 (41.8%)
43 (23.8%)
1
1
N.B indicates the determinant of neonatal jaundice at value <0.05. LBW: low birth weight, c/s: cesarean section, SVD: spontaneous vaginal delivery.