Rosuvastatin Improves Cognitive Function of Chronic Hypertensive Rats by Attenuating White Matter Lesions and Beta-Amyloid Deposits
Rosuvastatin ameliorated Aβ deposits in the cortex and hippocampus. (a) Representative images of Aβ protein accumulation in the frontal cortex. Scale bar: 25 mm. (b) Quantitative analysis of Ab deposits in the frontal cortex. (c) Representative images of Aβ protein accumulation in the hippocampus. Neurons were stained with NeuN (green). Aβ was stained with Aβ3-16 (red). Scale bar: 25 mm. (d) Quantitative analysis of Aβ deposits in the hippocampus. RHRSP/veh vs. sham-operated rats, .#RHRSP/ros vs. RHRSP/veh, . in RHRSP/veh and RHRSP/ros; in the sham-operated group.
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