The CC Genotype of Insulin-Induced Gene 2 rs7566605 Is a Protective Factor of Hypercholesteremia Susceptible to Mild Cognitive Impairment, Especially to the Executive Function of Patients with Type 2 Diabetes Mellitus

Table 2

Distributions of the INSIG-2 rs7566605 genotypes in T2DM patients with MCI or normal cognition.

Genotypes	MCI (, %)	Non-MCI (, %)	OR (95% CL)
All	87	146
G	114 (65.5)	165 (56.5)	1.000
C	60 (34.5)	127 (43.5)	1.462 (0.991-2.158)	0.055
GG	38 (43.7)	51 (34.9)	1.000
GC	38 (43.7)	63 (43.2)	1.235 (0.690-2.210)	0.476
CC	11 (12.6)	32 (21.9)	2.168 (0.971-4.841)	0.056
GC+CC	49 (56.3)	95 (65.1)	1.445 (0.839-2.487)	0.184

MCI: individuals with mild cognitive impairment; Non-MCI: individuals without mild cognitive impairment. The genotypes and allele frequencies were compared between the groups using Pearson’s tests.