Research Article
Mining Database for the Clinical Significance and Prognostic Value of ESRP1 in Cutaneous Malignant Melanoma
Table 2
Correlation analysis between ESRP1 and related genes and biomarkers of immune cells in CMM (TIMER).
| | Description | Gene markers | CMM | | None | Purity | | Cor | value | Cor | value |
| | CD8+ T cell | CD8A | -0.223 | | -0.143 | | | CD8B | -0.201 | | -0.114 | |
| | T cell (general) | CD3D | -0.215 | | -0.125 | | | CD3E | -0.227 | | -0.139 | | | CD2 | -0.226 | | -0.139 | |
| | B cell | CD19 | -0.196 | | -0.128 | | | CD79A | -0.185 | | -0.105 | |
| | Monocyte | CD86 | -0.352 | | -0.272 | | | CD115(CSF1R) | -0.37 | | -0.325 | |
| | TAM | CCL2 | -0.357 | | -0.314 | | | CD68 | -0.179 | | -0.121 | | | IL10 | -0.371 | | -0.325 | |
| | M1 macrophage | INOS (NOS2) | -0.057 | 0.219 | -0.046 | 0.326 | | IRF5 | -0.279 | | -0.214 | | | COX2(PTGS2) | -0.292 | | -0.273 | |
| | M2 macrophage | CD163 | -0.363 | | -0.317 | | | VSIG4 | -0.346 | | -0.294 | | | MS4A4A | -0.326 | | -0.266 | |
| | Neutrophils | CD66b (CEACAM8) | -0.042 | 0.361 | -0.054 | 0.251 | | CD11b (ITGAM) | -0.366 | | -0.317 | | | CCR7 | -0.215 | | -0.137 | |
| | Natural killer cell | KIR2DL1 | -0.156 | | -0.074 | 0.113 | | KIR2DL3 | -0.197 | | -0.119 | | | KIR2DL4 | -0.167 | | -0.085 | 0.068 | | KIR3DL1 | -0.188 | | -0.11 | | | KIR3DL2 | -0.232 | | -0.152 | | | KIR3DL3 | -0.046 | 0.317 | -0.012 | 0.795 | | KIR2DS4 | -0.12 | | -0.052 | 0.268 |
| | Dendritic cell | HLA-DPB1 | -0.253 | | -0.174 | | | HLA-DQB1 | -0.259 | | -0.191 | | | HLA-DRA | -0.276 | | -0.206 | | | HLA-DPA1 | -0.256 | | -0.186 | | | BDCA-1(CD1C) | -0.227 | | -0.161 | | | BDCA-4(NRP1) | -0.414 | | -0.388 | | | CD11c (ITGAX) | -0.242 | | -0.171 | |
| | Th1 | T-bet (TBX21) | -0.242 | | -0.159 | | | STAT4 | -0.204 | | -0.122 | | | STAT1 | -0.144 | | -0.075 | 0.111 | | IFN-g (IFNG) | -0.22 | | -0.144 | | | TNF-a (TNF) | -0.151 | | -0.055 | 0.241 |
| | Th2 | GATA3 | -0.16 | | -0.03 | 0.522 | | STAT6 | -0.327 | | -0.341 | | | STAT5A | -0.206 | | -0.221 | | | IL13 | -0.057 | 0.217 | -0.023 | 0.617 |
| | Tfh | BCL6 | -0.276 | | -0.27 | | | IL21 | -0.183 | | -0.132 | |
| | Th17 | STAT3 | -0.196 | | -0.153 | | | IL17A | -0.119 | | -0.141 | |
| | Treg | FOXP3 | -0.226 | | -0.145 | | | CCR8 | -0.254 | | -0.187 | | | STAT5B | -0.14 | | -0.14 | | | TGFb (TGFB1) | -0.393 | | -0.355 | |
| | T cell exhaustion | PD-1 (PDCD1) | -0.193 | | -0.103 | | | CTLA4 | -0.321 | | -0.273 | | | LAG3 | -0.206 | | -0.121 | | | TIM-3 (HAVCR2) | -0.331 | | -0.278 | | | GZMB | -0.232 | | -0.147 | |
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